Currently available opportunities in the laboratory are detailed below. For more information about any research project, please contact robert.baldock@port.ac.uk.

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Masters by Research (MRes) & Doctor of Philosophy (PhD)

Project title: Investigating mechanisms of mitochondrial and nuclear genome stability

Defects in cellular DNA repair mechanisms are associated with numerous human diseases, including cancer. The absence of these key pathways leads to increased genomic instability and altered cellular function. Research has identified a number of DNA repair proteins that protect nuclear DNA, they’re also localised in mitochondria – although their functional role remains unclear. This MRes project will help characterise the role of these proteins in protecting the mitochondrial and nuclear genomes, as well as identifying their potential role in disease progression. You’ll gain experience in a number of molecular biology and cell biology techniques and use bioinformatic approaches to generate and test novel insights.

For more information on this project, including how to apply, please visit: https://www.port.ac.uk/study/courses/postgraduate-taught/mres-science-and-health/mres-projects-pharmacy-and-biomedical-science#genome-stability and for PhD enquiries please email Robert.Baldock@port.ac.uk

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